API CAS 918504

Basic Info.

Model NO.	TY-02AL
Einecs	616-396-9
Shelf	2 Years
Assay	99%
Appearance	White Powder
CAS	918504-65-1
Transport Package	25kg/Drum 5g, 100g, 500g, 1kg, 10kg, 100kg, 200kg
Specification	25kg/drum
Trademark	tongyon
Origin	China
Production Capacity	5000kg/Month

Product Description

Product name	Vemurafenib
CAS	918504-65-1
Appearance	white powder
Assay	99%
Storage	Cool and Protect from light

Product Name:VemurafenibMF:C23H18ClF2N3O3SMW:489.9221264EINECS:Mol File:918504-65-1.mol Density 1.46form White powder.pka6.26±0.10(Predicted)

Chemical PropertiesOff-White SolidOriginatorPlexxikon (United States)UsesPLX4032 is an orally bioavailable, ATP-competitive inhibitor of mutant V600E and wild type B-Raf kinases (IC50s = 31 and 100 nM, respectively). It inhibits cell proliferation in a variety of cell lines expressing B-Raf V600E and synergizes strongly with taxol, vinblastine, and oxaliplatin in inhibiting the proliferation of B-RafV600E transformed cancer cells. PLX4032 is effective against the growth of tumors bearing the B-Raf V600E mutation.[Cayman Chemical]UsesVemurafenib selective BRAFV600E kinase inhibitor; an antitumor agent. Vemurafenib functions by inhibiting the proliferation and mitogen-activated protein/extracellular signal-regulated kinase (ERK) kinase and ERK phosphorylation in a panel of tumor cell lines, including melanoma cell lines expressing BRAFV600E or other mutant BRAF proteins altered at codon 600.UsesVemurafenib (PLX4032, RG7204) is a novel and potent inhibitor of B-RafV600E with IC50 of 31 nM
GuangZhou TongYi biochemistry technology Co.,LTD is a company specializing in active pharmaceutical ingredient (API), biology,plant extracts, chemical raw materials, fine chemicals, pharmaceutical intermediates, cosmetics raw material. Our company has always adhered to the company philosophy of integrity, professionalism, quality first, and customer service. With the efforts of all the company's employees, it has established long-term and stable cooperative relations with many domestic and foreign customers, and won the unanimous trust of domestic and foreign customers. With good comments, our company have made great progress.
Our company takes pioneering and innovative, high-quality and efficient as the code of conduct, and strives to providecustomers with efficient services,high-quality products, and reasonable prices. We have established a customer demand-oriented, flexible, diverse and customizable service according to the different needs of different customers. Mode, and ultimately achieve the goal ofwin-win.Our company focuses on the future and the world, and will continue to devote itself to technological progress and thedevelopment of new products in the future, hoping to work hand in hand with new and old friends at home and abroadto create a better future.